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The CTS-AMI Randomized Clinical TrialKey PointsQuestion Among patients with acute ST-segment elevation myocardial infarction (STEMI), does the addition of a traditional Chinese medicine compound (Tongxinluo) as an adjunctive treatment to guideline-directed therapies improve clinical outcomes?Findings In this randomized, double-blind, placebo-controlled clinical trial of 3777 patients with STEMI, oral administration of
