Olimestra

14/05/2024
13

Section bar: 
Olmesartan medoxomil: 10/20mg

Point:

– Treatment of hypertension in adults

– Treatment of hypertension in children and adolescents from 6 to 18 years old

INGREDIENT
Olmesartan medoxomil: 10/20mg
Excipients: Magnesium Stearate, Low-substituted Hydroxypropyl Cellulose, Microcrystalline Cellulose, Lactose monohydrate, Polyvinyl Alcohol-Part, Titanium Dioxide (E 171), Macrogol 3000, Talc.
PHARMACODYNAMIC
Olmesartan is a leading drug in a new class of antihypertensive drugs, a specific antagonist of angiotensin II receptor (type AT1)… Olmesartan has an affinity for the AT1 receptor 12,500 times that of the AT2 receptor so it can The Angiotensin receptor blocking effect of Olmesartan is highly selective. Olmesartan is a potent, oral, synthetic active ingredient that selectively binds to AT1 receptors. In vitro and in vivo, both olmesartan and its pharmacologically active metabolite (E-3174) block all physiological effects associated with angiotensin II, including vasoconstriction. , salt-water retention and sympathetic stimulation. This leads to a drop in blood pressure…
POINT
-Treatment of hypertension in adults
-Treatment of hypertension in children and adolescents aged 6 to 18 years
DOSAGE AND HOW TO USE
-Recommended dose to start with 10mg per day
In patients whose blood pressure is not controlled at this dose, the dose may be increased to 20 mg/day as the optimal dose.
The maximum dose is 40mg per day.
CONTRAINDICATIONS
-Patients with hypersensitivity to any component of the drug
-Patient is pregnant in the second and third months of pregnancy
-Closed Secrets
-Concomitant use of Olimestra with products containing aliskiren is contraindicated in patients with diabetes mellitus or renal impairment (GFR <60 mL/min/1.73 m2)
PACKING
Box of 2 blisters x 15 film coated tablets
Storage conditions: Store in a dry place, protected from light and moisture, at a temperature below 300C.
Producer
KRKA, D.D., NOVO MESTO
8501 Novo mesto, Slovenia, EU.

POINT

- Treatment of hypertension in adults

- Treatment of hypertension in children and adolescents from 6 to 18 years old

DOSAGE AND HOW TO USE

- Recommended starting dose is 10mg per day

- In patients whose blood pressure is not controlled at this dose, the dose may be increased to 20 mg/day as the optimal dose.

- Maximum dosage 40mg per day.

CONTRAINDICATIONS

- Patients who are hypersensitive to any ingredient of the drug

- Patients in the second and last 3 months of pregnancy

- Bile obstruction

- Concomitant use of Olimestra with aliskiren-containing products is contraindicated in patients with diabetes or renal impairment (GFR <60 mL/min/1.73 m2).

PACKING

Box of 2 blisters x 15 film-coated tablets

Storage conditions: Store in a dry place, away from light and moisture, at temperature below 30oC.

Sản phẩm: Olimestra
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